The Cranes are pooled in Group E alongside Mali and neighbors Kenya and Rwanda.
The quest for a first-ever appearance at the global showpiece will begin with a trip to Nairobi to face Kenya between 5th-8th June 2021.
Uganda will then return to action with a home fixture against Mali on matchday two. The dates will be between 11th -14th June.
Matchday three and four will be a doubleheader against Rwanda with the first leg coming between 1st -4th September in Kigali before facing off in Kampala in a space of two-three days.
The penultimate game will see Uganda host Kenya in the first week of October and later end the group phase with a trip to Bamako, Mali between 10th-12th October.
The group winner after six games will go into the final qualifying phase that will have nine other group leaders.
There will be a draw for the final ten teams and the five winners on aggregate will represent Africa at the 2022 FIFA World Cup in Qatar next year.
2022 World Cup Fixture
5th – 8th June, 2021
Kenya Vs Uganda
11th – 14th June 2021
Uganda Vs Mali
1st – 4th Sept 2021
Rwanda Vs Uganda
5th – 7th Sept 2021
Uganda Vs Rwanda
6th – 9th Oct 2021
Uganda Vs Kenya
10th – 12th Oct 2021
Mali Vs Uganda